• The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection 

      Dobrovolska, Olena; Brilkov, Maxim; Madeleine, Noëlly; Ødegaard-Fougner, Øyvind; Strømland, Øyvind; Martin, Stephen R.; De Marco, Valeria; Christodoulou, Evangelos; Teigen, Knut; Isaksson, Johan; Underhaug, Jarl; Reuter, Nathalie; Aalen, Reidunn B.; Aasland, Rein; Halskau, Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-21)
      Chromatin post‐translational modifications are thought to be important for epigenetic effects on gene expression. Methylation of histone N‐terminal tail lysine residues constitutes one of many such modifications, executed by families of histone lysine methyltransferase (HKMTase). One such protein is ASHH2 from the flowering plant <i>Arabidopsis thaliana</i>, equipped with the interaction domain, CW, ...
    • Justify your alpha 

      Lakens, Daniel; Adolfi, Federico G; Albers, Casper J; Anvari, Farid; Apps, M A J; Argamon, Shlomo E; Baguley, Thom; Becker, Raymond B; Benning, Stephen D; Bradford, D E; Buchanan, Erin M; Caldwell, Aaron R; Calster, Ben van; Carlsson, Rickard; Chen, Sau-Chin; Chung, Bryan; Colling, Lincoln J; Collins, G S; Crook, Zander; Cross, Emily S; Daniels, Sameera; Danielsson, Henrik; DeBruine, Lisa; Dunleavy, Daniel J; Earp, Brian D; Feist, Michele I; Ferrell, Jason D; Field, James G; Fox, Nicholas W; Friesen, Amanda; Gomes, Caio; Gonzalez-Marquez, Monica; Grange, James A; Grieve, Andrew P; Guggenberger, Robert; Grist, James; van Harmelen, Anne-Laura; Hasselman, Fred; Hochard, Kevin D; Hoffarth, Mark R; Holmes, Nicholas; Ingre, Michael; Isager, Peder Mortvedt; Isotalus, Hanna K; Johansson, Christer; Juszczyk, Konrad; Kenny, David; Khalil, Ahmed; Konat, Barbara; Lao, Junpeng; Larsen, Erik Gahner; Lodder, Gerine M A; Lukavsky, Jiri; Madan, Christopher R; Manheim, David; Martin, Stephen R.; Martin, Andrea E; Mayo, Deborah G; McCarthy, Randy; McConway, Kevin; McFarland, Colin; Nio, Amanda Q X; Nilsonne, Gustav; de Oliveira, Cilene Lino; de Xivry, Jean-Jacques Orban; Parsons, Sam; Pfuhl, Gerit; Quinn, Kimberly A; Sakon, John J; Saribay, S Adil; Schneider, Iris K; Selvaraju, Manojkumar; Sjoerds, Zsuzsika; Smith, Samuel G; Smits, Tim; Spies, Jeffrey R; Sreekumar, Vishnu; Steltenpohl, Crystal N; Stenhouse, Neil; Swiatkowski, Wojciech; Vadillo, Miguel A; Van Assen, Marcel A. L. M.; Williams, Matt; Williams, Samantha E; Williams, Donald R.; Yarkoni, Tal; Ziano, Ignazio; Zwaan, Rolf A (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-26)
      In response to recommendations to redefine statistical significance to p ≤ .005, we propose that researchers should transparently report and justify all choices they make when designing a study, including the alpha level.